About Regenear

History and Concept

Thanks to my daughter Andrea’s birth with microtia, my friendship with Dr. Balcells at MIT and Professor Elazer’s experience with tissue regeneration, the three of us came together to found Regenear in 2010. We believe that the field of facial cartilage regeneration is ready for commercialization for the benefit of many people around the globe.

Spun out of a joint laboratory at the Massachusetts Institute of Technology and Harvard Medical School, Regenear is developing a technique to grow an entirely new, patient specific ear. By using a sample of the patient’s own cartilage cells, we eliminate the need for painful rib graft surgeries and the fragility of prosthetics.

Regenear’s strategy builds off of key advances made in Dr. Vacanti’s laboratory at MIT. He is now one of the key supporters of the company and his research findings can be turned into an efficient system for regenerating ears with two years of dedicated development. With sufficient financial backing we expect this technology to be ready for application by 2020.

The amazing side benefit to our work is that the same techniques used to grow ear cartilage can be used to grow cartilage for nasal and chin reconstruction surgeries as well.

Steps to Regenerating an Ear 



The first step is to extract a small sample of a patient’s cartilage and purify out a group of cell’s known as chondrocytes. These are the workhorses that will be responsible for producing the cartilage of the new ear.


The purified chondrocytes are then seeded onto a biodegradable, hydrogel scaffold in a mold shaped like an ear. The matrix allows the cells to grow in an orderly fashion while maintaining their chondrocytic identity.


In a bioreactor that simulates in-vivo conditions, the cells populate the matrix, eventually replacing the hydrogel scaffold with their own cartilaginous network.


Once the ear has fully matured in the bioreactor it is ready for surgical attachment.